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Abstract #2077

Vessel Wall Thickness Evolution Across the Lifespan Assessed using Non-invasive Intracranial Vessel Wall Imaging

Petrice M Cogswell1, Sarah K Lants1, L Taylor Davis1, Spencer Waddle1, and Manus J Donahue1

1Vanderbilt University Medical Center, Nashville, TN, United States

Vessel wall imaging is becoming more widely applied, however normal, age-specific ranges for wall thickness have not been established. We applied a variable refocusing angle 3D-TSE acquisition with and without a DANTE flow suppression module to healthy subjects (ages=8-79 years; n=82). Vessel wall measurements revealed no significant change in wall thickness with age for the supraclinoid internal carotid arteries and basilar artery. The outer wall diameter and wall thickness were measured to be less for the acquisition with versus without DANTE. These data suggest that unlike tissue volume, vessel wall thickness is relatively constant across the lifespan for healthy subjects.

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