Concept of Gadolinium-Ferritin Interactions as Explanation of Signal Intensity Changes in Deep Brain Nuclei after Application of Gadolinium-Based Contrast Agents
Josef Vymazal1, Jitka Neburkova2, Martin Dracinsky2, Mohan Pingle3, Petr Cigler4, and Aaron Michael Rulseh1
1Dept. of Radiology, Na Homolce Hospital, Prague, Czech Republic, 2Insittute of Organic Chemistry and Biochemistry, Prague, Czech Republic, 3Dept. of Radiology, Na Homolce Hospital, Praha, Czech Republic, 4Petr Cigler, Insittute of Organic Chemistry and Biochemistry, Prague, Czech Republic
Interaction between gadolinium-based contrast agents and metalloprotein ferritin may explain observed signal intensity changes in vivo due to T1 (and T2) shortening in the globus pallidus and dentate nucleus.
This abstract and the presentation materials are available to members only;
a login is required.