Using contrast agent in fMRI has the benefits of providing additional information of regional cerebral blood volume (CBV) and of enhancing sensitivity. Response comparisons of BOLD and MION enhanced CBV fMRI to the noxious stimulus in non-human primate showed signal increase for MION fMRI in the regions that are important in pain-processing network. Activities of some brain areas, including putamen, were captured with MION fMRI, not with BOLD. Capsaicin treatment augmented the responses of fMRI to the noxious stimulation for BOLD and MION fMRI. New insight can be obtained for the pain network through the comparison between BOLD and CBV fMRI.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords