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Abstract #2129

In-Vivo Analysis of the Superficial White Matter in the Macaque Brain Using High-resolution Diffusion MRI: preliminary results

Yann Bihan-Poudec1, Slimane Tounekti1, Nathalie Richard1, Mathilda Froesel1, Franck Lamberton2, Thomas Troalen3, Suliann Ben Hamed1, Maxime Descoteaux4, and Bassem Hiba1

1CNRS, Bron, France, 2CERMEP, Bron, France, 3Siemens-Healthineers, Saint-Denis, France, 4Université de Sherbrooke, Sherbrooke, QC, Canada

This study was focused on the U-fibers located on the Superficial White Matter (SWM) of the Rhesus macaque brain.

A diffusion MRI (dMRI) pulse-sequence with a 3D multi-shot-EPI module was used to achieve a 0.5 mm isotropic dMRI data in 4 macaques.

The organization of white matter in the region of arcuate sulcus (AS) was analyzed using diffusion tensor and fiber orientation distribution data, the U-fiber over all the AS was tracked and its water diffusion metrics were quantitatively assessed.

The results, obtained using high-resolution dMRI, pave the way for quantitative analyses of SWM for clinical and neuroscientific applications.

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