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Abstract #2139

Quality of Life, Neurocognitive Function and T2 FLAIR Hyperintensity Volume in Stable Grade II and III Glioma Patients

Angela Jakary1, Tracy Luks1, Susan Chang2, Jennifer Clarke2, Nicholas Butowski2, Nancy Ann Oberheim Bush2, and Jennie Taylor2

1Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, 2Neurological Surgery, UCSF, San Francisco, CA, United States

Quality of life and neurocognitive function are important clinical outcome measures for patients with lower grade glioma. In this pilot study, we performed neurocognitive testing and quality of life assessments in radiologically and clinically stable grade II and III glioma patients who were not receiving active treatment. We found novel associations between standard clinical assessments and neuroimaging metrics at pre-surgical and follow-up timepoints. Further characterizing the longitudinal relationship between structural and functional neuroimaging, neurocognition and quality of life will better allow clinicians to proactively intervene to help patients in future.

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