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Abstract #2138

Gadolinium concentration map based on synthetic MRI and its application to brain metastases

Misaki Nakazawa1, Akifumi Hagiwara1,2, Christina Andica1, Masaaki Hori1, Moeko Horita1,3, Koji Kamagata1, Haruyoshi Houshito1, and Shigeki Aoki1

1Department of Radiology, Juntendo University School of Medicine School of Medicine School of Medicine, Tokyo, Japan, 2Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 3Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan

Signal intensity measured on T1-weighted image is not proportional to the gadolinium concentration in vivo after administration of contrast agent. Thus, some calculations are required to estimate gadolinium concentration using quantitative values before and after gadolinium administration. We created gadolinium concentration maps that directly show the amount of contrast agent using quantitative maps calculated using synthetic MRI. The gadolinium concentration map we created using phantoms showed high accuracy and precision. The gadolinium concentration map could reliably measure the concentration of gadolinium in metastatic brain tumors.

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