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Abstract #2181

Quantitative Modeling of Sequence Parameter Choices to Support Standardization for Quantitative DCE-MRI

Jakob Meineke1 and Jochen Keupp1

1Philips Research Europe, Hamburg, Germany

Systematic and statistical errors in quantitative DCE-MRI measurements which adhere to standardization recommendations by the Quantitative Imaging Biomarker Alliance (QIBA) of the RSNA are assessed using EPG simulations. It is found that small sequence parameter changes, well within the bounds allowed by QIBA, can produce large changes in the estimated quantitative parameters.

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