In Susceptibility Mapping (SM) using multi-echo acquisitions, noise propagates from the single-echo phase images into the field map in a manner dependent on the method used for multi-echo combination. Field noise then propagates into the susceptibility map, determining the precision of the measured susceptibility. Here, we characterised the propagation of single-echo phase noise into both the combined field and susceptibility maps using three methods for multi-echo combination: fitting, averaging and echo time-weighted averaging. We calculated susceptibility noise maps for both simulated and acquired data, showing that, when choosing a pipeline for multi-echo SM, it is important to consider its precision.
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