The direction of the external magnetic field is typically fixed, although it is well-known that the signal of various MR modalities in brain white matter depends on the magnetic field direction. This work presents a general framework for analysing B0-direction dependent contrast. Specifically, we have developed a holder device, called BuckyBall, that enables the uniform orientation of the scanned object in a reproducible manner. Its feasibility and practicality are demonstrated in a multi-echo gradient-echo experiment with 50 unique magnetic field directions using a monkey brain sample.
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