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Abstract #2209

BuckyBall: Reproducible gradient-echo MRI measurements with variable magnetic field directions

Enrico Kaden1, Irina Y. Barskaya2, Nathaniel D. Kelm2, Mark D. Does2, and Daniel C. Alexander1

1Centre for Medical Image Computing, Department of Computer Science, University College London, London, United Kingdom, 2Institute of Imaging Science, Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States

The direction of the external magnetic field is typically fixed, although it is well-known that the signal of various MR modalities in brain white matter depends on the magnetic field direction. This work presents a general framework for analysing B0-direction dependent contrast. Specifically, we have developed a holder device, called BuckyBall, that enables the uniform orientation of the scanned object in a reproducible manner. Its feasibility and practicality are demonstrated in a multi-echo gradient-echo experiment with 50 unique magnetic field directions using a monkey brain sample.

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