Abstract #2232

CEST Feasibility in Rectal Cancer Patients at 7T for Detection of Residual Tumor

Catalina S. Arteaga de Castro¹, Quincy van Houtum¹, Sieske Hoendervangers², Alice M Couwenberg², Martijn P.W. Intven², Helena M Verkooijen^2,3, Dennis W.J. Klomp¹, and Marielle E.P. Philippens²

¹Imaging, University Medical Center Utrecht, Utrecht, Netherlands, ²Radiation Oncology, University Medical Center Utrecht, Utrecht, Netherlands, ³Utrecht University, Utrecht, Netherlands

Five patients were scanned at a 7T MR scanner, 9 weeks after chemoradiation treatment. Three patients showed extreme artifacts on the calculated CEST maps due to B0 artifacts from air contained in the rectum or poor B0 shimming. Two successful CEST measurements showed matching amide-CEST maps to the residual tumor observed in the MRI. CEST applied to rectum patients after chemoradiation might be the appropriate technique to avoid surgical resection in some patients without residual tumor after treatment.

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