Abstract #2249

Low power Z-spectrum analysis for isolated NOE and amide CEST-MRI at 3T with comparison to 9.4T

Anagha Deshmane¹, Moritz Zaiss¹, Benjamin Bender², Tobias Lindig², Johannes Windschuh³, Kai Herz¹, and Klaus Scheffler¹

¹High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, ²Diagnostic & Interventional Neuroradiology, University Hospital Tuebingen, Tuebingen, Germany, ³Center for Biomedical Imaging, New York University Langone Health, New York, NY, United States

A snapCEST sequence was optimized for imaging of protein CEST effects at 3T with low saturation power. Full Z-spectrum sampling allows Lorentzian fitting of amide, NOE, semisolid MT, and water pools. Validation against data acquired at 9.4T demonstrates effective labeling of selective amide and NOE CEST effects at 3T. Data acquired in a brain tumor patients demonstrates clinical feasibility.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.