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Abstract #2261

Tomoelastography of pancreatic tumors: Preliminary results

Stephan Rodrigo Marticorena Garcia1, Christian Burkhardt1, Rosa Schmuck2, Guo Jing1, Bernd Hamm1, Jürgen Braun3, and Ingolf Sack1

1Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Experimental Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

High-resolution stiffness maps of the pancreas were generated using multifrequency magnetic resonance elastography (MRE) and tomoelastography data processing in healthy controls (Ctr) and patients with pancreatic carcinoma (Pa-Ca). Pa-Ca have higher stiffness than control tissue and non-tumorous pancreatic parenchyma in patients without overlap to normal values. Subregional analysis for pancreatic head, corpus and tail revealed no difference between these anatomical regions. Tomoelastogaphy is sensitive to pathological changes in viscoelastic properties of Pa-Ca and offers a quantitative measure of stiffness of pancreatic tissue.

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