High-resolution stiffness maps of the pancreas were generated using multifrequency magnetic resonance elastography (MRE) and tomoelastography data processing in healthy controls (Ctr) and patients with pancreatic carcinoma (Pa-Ca). Pa-Ca have higher stiffness than control tissue and non-tumorous pancreatic parenchyma in patients without overlap to normal values. Subregional analysis for pancreatic head, corpus and tail revealed no difference between these anatomical regions. Tomoelastogaphy is sensitive to pathological changes in viscoelastic properties of Pa-Ca and offers a quantitative measure of stiffness of pancreatic tissue.
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