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Abstract #2263

MR Elastography of Kidneys Using SE-EPI: A Reproducibility Study and Comparison to ADC and FA Measurements

Deep Gandhi1, Prateek Kalra2, Huiming Dong1, Brian Raterman2, and Arunark Kolipaka2

1Biomedical Engineering, Ohio State University, Columbus, OH, United States, 2Radiology, Ohio State University Wexner Medical Center, Columbus, OH, United States

Stiffness change has been associated with progress of disease. Magnetic resonance elastography(MRE) is an imaging-based alternative that can measure stiffness. Diffusion Tensor Imaging(DTI) provides apparent diffusion coefficient(ADC) and fractional anisotropy(FA) of the tissue. Previous studies have investigated stiffness and diffusion in kidneys individually. However, none of the studies have investigated the two together. Aim of this study is to show reproducibility of spin-echo echo-planar imaging(SE-EPI) MRE and correlate it with ADC and FA measurements obtained from DTI. Preliminary results showed good reproducibility in stiffness measurements and moderate correlation between MRE stiffness and ADC and FA values from DTI.

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