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Abstract #2307

Arousal-related fMRI modulations contribute to the effect of the motion-based scrubbing on local and long-range connectivity

Yameng Gu1 and Xiao Liu1

1Biomedical Engineering, Pennsylvania State University, State College, PA, United States

Head motion has been shown to be associated with distinct changes in local and long-range rsfMRI connectivity, and the temporal scrubbing based on motion parameters has been proposed to remove such “motion-induced” artefacts. Here, we showed that scrubbing arousal-related time points resulted in a similar but stronger change on the rsfMRI connectivity than the motion-based scrubbing. Moreover, the effect of the motion-based scrubbing can be completely removed by retaining the part of scrubbed time points related to arousal changes. The findings suggest that arousal modulations may mediate the association between the motion and rsfMRI connectivity.

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