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Abstract #2306

Sex Differences in Stimulus Induced Blood Flow: The Importance of Sex Hormones

Samantha Cote1, Russell Butler1, Jean-Francios Lepage1, Adrianna Mendrek2, and Kevin Whittingstall1

1Université de Sherbrooke, Sherbrooke, QC, Canada, 2Bishop's University, Sherbrooke, QC, Canada

Sex differences in resting CBF has been reported, these differences may be explained through sex differences in sex hormones. There is currently no study that examines if this difference is maintained during stimulus-induced CBF. The current study evaluated men and naturally cycling women three times during their menstrual cycle at different sex hormone levels using a pCASL sequence. Preliminary results reveal sex differences in CBF response to the same stimulus, which is amplified when one considers sex hormones. These findings may reflect vascular effects of sex hormones, highlighting the importance of considering sex and hormone profiles when conducting fMRI

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