Abstract #2336

The case for 3D PRESTO fMRI: Improved temporal SNR via ghost suppression by temporal filtering

Jon-Fredrik Nielsen¹, Tianrui Luo¹, Scott J Peltier¹, and Douglas C Noll¹

¹Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

We apply a recently-introduced method for more efficient RF-spoiling in dynamic imaging to PRESTO fMRI, and show that this improves temporal SNR significantly. For a whole-brain fMRI acquisition with high temporal resolution (TR_vol=0.52s) and 3.3mm isotropic resolution, tSNR is maximized for a net gradient area of only about 1-1.5 cycles/voxel (applied to two gradient axes). We anticipate that the use of such low spoiler gradients will make PRESTO a much more viable alternative for 3D fMRI.

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