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Abstract #2350

Alterations of neural activity patterns in pontine versus coronal radiata stroke

Chunxiang Jiang1,2, Siqi Cai1,2, Rui Meng1,2, Xiaojing Long1, Hang Zhang1, and Lijuan Zhang*1

1Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 2University of Chinese Academy of Sciences, Beijing, China

We compared the alteration of intrinsic neural functional networks in 15 patients with ischemic stroke (IS) in pontine (PS) and 21 patients with IS in coronal radiata (CRS) with 30 healthy controls (HCs). Degree centrality (DC) increased in posterior cingulate gyrus and ReHo decreased in sensorimotor cortex and default mode network in PS and CRS group relative to HCs group. DC increase was observed in cuneus in CRS group. These findings suggest that IS disrupts the functional integration of brain in an extensive scale, and the lesion location may substrate the functional outcomes for the IS patients.

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