Abstract #2379

Simultaneous acquisition of $$$T_1$$$ Maps and BOLD fMRI Signal During Brain Activation Using Multi-Echo EPI

Xianglun Mao¹, J. Andrew Derbyshire², Vinai Roopchansingh², Thomas M Talavage^1,3, and Peter A Bandettini ²

¹School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN, United States, ²Functional MRI facility, NIMH, National Institute of Health, Bethesda, MD, United States, ³Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States

A quantitative $$$T_1$$$ map and blood oxygenation level-dependent (BOLD) signals are simultaneously measured during a flickering checkerboard using a multi-echo echo-planar imaging (ME-EPI) based fMRI sequence. The acquired EPI-based $$$T_1$$$ maps provide a means of tissue identification and allow direct comparison with BOLD activation maps on a voxel-wise basis, and thus offer an alternative of tissue segmentation and avoid the need for image registration between anatomical and functional imaging data

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