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Abstract #2379

Simultaneous acquisition of $$$T_1$$$ Maps and BOLD fMRI Signal During Brain Activation Using Multi-Echo EPI

Xianglun Mao1, J. Andrew Derbyshire2, Vinai Roopchansingh2, Thomas M Talavage1,3, and Peter A Bandettini 2

1School of Electrical and Computer Engineering, Purdue University, West Lafayette, IN, United States, 2Functional MRI facility, NIMH, National Institute of Health, Bethesda, MD, United States, 3Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States

A quantitative $$$T_1$$$ map and blood oxygenation level-dependent (BOLD) signals are simultaneously measured during a flickering checkerboard using a multi-echo echo-planar imaging (ME-EPI) based fMRI sequence. The acquired EPI-based $$$T_1$$$ maps provide a means of tissue identification and allow direct comparison with BOLD activation maps on a voxel-wise basis, and thus offer an alternative of tissue segmentation and avoid the need for image registration between anatomical and functional imaging data

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