Abstract #2380

Comparing cortical layer activation using gradient echo with phase regression and spin echo in the human visual cortex

Olivia W Stanley^1,2, Alan B Kuurstra², L Martyn Klassen^1,2, Ravi S Menon^1,2, and Joseph S Gati^1,2

¹Medical Biophysics, The University of Western Ontario, London, ON, Canada, ²Centre for Functional and Metabolic Mapping, The University of Western Ontario, London, ON, Canada

High resolution fMRI sequence selection is often a compromise between specificity to tissue (SE-EPI) and sensitivity to the BOLD effect (GE-EPI). Our work compared the laminar activation profiles of SE-EPI and GE-EPI once phase regression based macrovascular filtering has been applied. We demonstrated that GE-EPI with macrovascular filtering produces a laminar profile more similar to SE-EPI than GE-EPI without filtering. This shows that GE-EPI could be used for high resolution imaging and achieve a more sensitive profile when phase regression is included.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.