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Abstract #2386

More than BOLD: dual spin populations create functional contrast

David Ress1, Elizabeth Halfen1, Vimal Singh2, and Amanda Taylor1

1Neuroscience, Baylor College of Medicine, Houston, TX, United States, 2Electrical Engineering, University of Texas at Austin, Austin, TX, United States

The "classical" description of functional contrast postulates a single spin population with transverse lifetime modulated by neurovascular coupling. A variety of studies have cast doubt on this description. To better understand such issues, novel methods were used to probe functional contrast in the gray matter of human visual cortex as a function of echo time and flip angle. We find evidence that two spin populations with disparate lifetimes contribute to functional contrast.

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