Abstract #2401

Functional connectivity sensitivity to image acceleration and orientation in simultaneous PET/MRI

Alessandro Palombit^1,2, Marco Castellaro^1,2, Erica Silvestri^1,2, Enrico De Vita³, Diego Cecchin^2,4, and Alessandra Bertoldo^1,2

¹Department of Information Engineering, University of Padova, Padova, Italy, ²Padova Neuroscience Center, University of Padova, Padova, Italy, ³Department of Biomedical Engineering, King's College London, London, United Kingdom, ⁴Department of Diagnostic Medical Sciences, University of Padova, Padova, Italy

Resting state fMRI (rs-fMRI) permits in-vivo characterization of brain’s functional connectivity (FC). Multi-Band accelerated EPI allows to improve the temporal resolution of rs-fMRI data and, potentially, to achieve a better characterization of the brain network correlations. However, the impact of image acceleration and orientation on FC structure has not been quantified. In this work we investigated FC changes related to image acceleration effects in a test/retest rs-fMRI protocol. We found FC differences involving relevant networks, confirmed even by graph analysis of the FC maps. Our findings explore the lower bound of single-subject FC reliability and network-dependent acceleration sensitivity.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.