Abstract #2409

Improving the resting state fMRI detection in anesthetized monkeys using multiband MRI technique

Chun-Xia Li¹, Doty Kempf¹, Leonard Howell^1,2, and Xiaodong Zhang^1,2

¹Yerkes Imaging Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States, ²Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States

Neuroimaging studies of non-human primates are generally conducted with anesthesia using anesthetics like isoflurane which is known to suppress the neuronal activation of the brain substantially. The resting state functional MRI (rsfMRI) examination in anesthetized monkeys is hindered by limited choices of anesthetics compared to rodent studies. In the present study, multiband MRI technique was explored to improve the rsfMRI detection in anesthetized macaque monkeys. The preliminary results suggest the multiband MRI can be employed to dramatically improve the rsfMRI detection in examining the functional connectivity of default mode network in anesthetized monkeys using a clinical 3T setting.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.