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Abstract #2419

Rapid and Simultaneous T1, T2 and Diffusion Quantification using MR Fingerprinting in the Breast

Yun Jiang1, Katherine L. Wright1, Jesse Hamilton2, Wei-Ching Lo2, Ananya Panda1, Gregor Körzdörfer3,4, Shota Hodono5, Michael A. Boss6, Nicole Seiberlich1,2, Vikas Gulani1,2, and Mark A. Griswold1,2

1Radiology, Case Western Reserve University, Cleveland, OH, United States, 2Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 3Siemens Healthcare GmbH, Erlangen, Germany, 4Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany, 5Department of Physics and Astronomy, Ohio Northern University, Ada, OH, United States, 6National Institute of Standards and Technology, Boulder, CO, United States

High quality, distortion-free T1, T2 and diffusivity maps in breast imaging are simultaneously generated using MRF framework. A good agreement of T1, T2 and ADC between the proposed MRF method and the traditional spin echo methods is demonstrated in a phantom and in vivo in breast imaging. This method enables the simultaneous collection of T1, T2 and diffusion maps for tissue characterization without the need to co-register separately acquired maps as in conventional MRI.

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