Abstract #2419

Rapid and Simultaneous T1, T2 and Diffusion Quantification using MR Fingerprinting in the Breast

Yun Jiang¹, Katherine L. Wright¹, Jesse Hamilton², Wei-Ching Lo², Ananya Panda¹, Gregor Körzdörfer^3,4, Shota Hodono⁵, Michael A. Boss⁶, Nicole Seiberlich^1,2, Vikas Gulani^1,2, and Mark A. Griswold^1,2

¹Radiology, Case Western Reserve University, Cleveland, OH, United States, ²Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ³Siemens Healthcare GmbH, Erlangen, Germany, ⁴Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany, ⁵Department of Physics and Astronomy, Ohio Northern University, Ada, OH, United States, ⁶National Institute of Standards and Technology, Boulder, CO, United States

High quality, distortion-free T1, T2 and diffusivity maps in breast imaging are simultaneously generated using MRF framework. A good agreement of T1, T2 and ADC between the proposed MRF method and the traditional spin echo methods is demonstrated in a phantom and in vivo in breast imaging. This method enables the simultaneous collection of T1, T2 and diffusion maps for tissue characterization without the need to co-register separately acquired maps as in conventional MRI.

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