There was the time when contrast enhancement was critical to identify and differentiate malignant from benign tumor, but as the field of MR has made strides towards advanced imaging, we now can use the methods which doesn't require contrast. It is especially helpful in end stage renal patients. As the world demographic is slowly tilting towards geriatric population it will soon become essential to come up with alternative ways to detect the malignant pathologies independent of exogenous contrast. In our study we have demonstrated by plotting the ROC curve that ASL and DTI are promising methods to detect breast cancer.
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