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Abstract #2429

Breast phyllodes tumor: histogram analysis of the apparent diffusion coefficient for assessment of tumor grading

Wenrui Tang1, Yan Zhang1, Dandan Zheng2, and Jingliang Cheng1

1Department of MRI, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2GE Healthcare, China, Beijing, China

Phyllodes tumors are uncommon, biphasic, fibroepithelial lesions of the breast, characterized by leafy stromal fronds capped by benign bilayered epithelium. Grading of breast phyllodes tumors is critical for diagnosis, treatment options and preoperative evaluation. This study is to assess the feasibility of diffusion weighted image (DWI) for determining phyllodes tumors grades in the femoral breast. Our results reveal that histogram analysis of apparent diffusion coefficient (ADC) parameters derived from DWI can be used to classify the benign and malignant breast phyllodes tumors patients. This can be applied for clinical diagnose and treatment.

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