Abstract #2443

A Study of Lung Function Variability in Chronic Obstructive Pulmonary Disease Using Hybrid Hyperpolarized 3He Imaging

Hooman Hamedani¹, Ryan Baron¹, Sarmad Siddiqui¹, Yi Xin¹, Mary Spencer¹, Faraz Amzajerdian¹, Stephen Kadlecek¹, Kai Ruppert¹, Mehrdad Pourfathi¹, Luis Loza¹, Ian Duncan¹, Tahmina Achekzai¹, Maurizio Cereda², and Rahim R. Rizi¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States

To better understand variable lung function in COPD, we imaged a subset of COPDGene subjects at baseline, one week post-baseline and one month post-baseline using a multifaceted hyperpolarized (HP) ³He scheme to measure apparent diffusion coefficient (ADC), fractional ventilation (FV), alveolar oxygen tension (P_AO₂) and oxygen uptake (R) variability.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.