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Abstract #2457

Implementation of the FLORET Ultrashort Echo-Time Sequence for Lung Imaging

Matthew M. Willmering1, Ryan K. Robison2, Hui Wang3, James G. Pipe4, and Jason C. Woods1,5

1Center for Pulmonary Imaging Research, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States, 2Phoenix Children’s Hospital, Phoenix, AZ, United States, 3Philips Healthcare, Gainesville, FL, United States, 4Barrow Neurological Institute, Phoenix, AZ, United States, 5Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States

MRI of lungs is inherently challenging due to the short T2* and intrinsic motion from the respiratory and cardiac cycles. Ultrashort echo-time (UTE) sequences are often implemented for their shorter echo times and relative insensitivity to motion. Spiral UTE sequences have been touted recently as having greater k-space sampling efficiencies than radial UTE, but few are designed well for the shorter T2* of lung. In this study, FLORET (Fermat looped, orthogonally encoded trajectories), a recently-developed spiral 3D UTE sequence, was implemented in human lungs for the first time and outperformed traditional radial UTE for imaging of lung tissue.

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