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Abstract #2464

Temporal and spatial evaluation of pulmonary blood flow using multiple delay PCASL at 1.5 Tesla

Ferdinand Seith1, Rolf Pohmann2, Martin Schwartz3,4, Thomas Küstner3,4, Klaus Scheffler2,5, Konstantin Nikolaou1, Fritz Schick3, and Petros Martirosian3

1Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany, 2Max Planck Institute for Biological Cybernetics, Tübingen, Germany, 3Section on Experimental Radiology, University of Tübingen, Tübingen, Germany, 4Institute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany, 5Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

Pseudo-continuous-arterial-spin-labeling (PCASL) has been successfully applied in abdominal organs to image organ perfusion. The aim of this work was to evaluate the pulmonary blood flow in dependence on the cardiac cycle using PCASL at 1.5T. Labeling of pulmonary blood flow was achieved by ECG triggering and an labeling plane perpendicular to the pulmonary trunk (tagging duration 300ms). In five volunteers, eight measurements were acquired with fast True-FISP imaging (in-plane-resolution, 2.5×2.5mm2, coronal view) with post-labeling delays between 100 and 1500ms. The PCASL-True-FISP technique was able to precisely assess blood flow of pulmonary arteries, as well as perfusion of the lung parenchyma.

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