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Abstract #2465

GRE bSSFP vs. FLASH based Fourier Decomposition lung MRI at 1.5T: evaluation of image quality, fractional ventilation and lung perfusion in healthy volunteers

Alexander Rotärmel1,2, Andreas Voskrebenzev1,2, Filip Klimes1,2, Marcel Gutberlet1,2, Frank Wacker1,2, and Jens Vogel-Claussen1,2

1Institute of Diagnostic and Interventional Radiology, Medical School Hannover, Hannover, Germany, 2German Center for Lung Research, Hannover, Germany

The comparison between different MRI sequences for assessment of lung ventilation and perfusion using phase-resolved functional lung MRI post-processing (PREFUL) needs further evaluation to support clinical translation. Our study compares two gradient echo (GRE) balanced steady state free precession (bSSFP) sequences (one commercially available and one modified by Bauman et al.) and one GRE Fast Low Angle Shot (FLASH) sequence regarding signal-to-noise ratio, fractional ventilation and lung perfusion. In summary, the bSSFP sequence modified by Bauman provides significantly higher SNR values and better perfusion values in the lung parenchyma compared to the commercially available bSSFP and FLASH sequences using PREFUL.

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