Preoperative characterization of the renal lesions has clinical significance in determining the appropriate treatment strategy and evaluating prognosis. The current study aims to investigate the potential of multiparametric DWI models, including monoexponential, biexponential, stretched-exponential, and kurtosis models in distinguishing between benign and malignant renal lesions, different tumor types as well as different grading of RCC. Compared with monoexpontial model, these highly parameterized non-Gaussian diffusion models may provide more information in the characterization of renal lesions, which would be helpful in improving therapy strategies and prognoses in the future, and further evaluation are required.
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