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Abstract #2491

Intravoxel incoherent motion-diffusion weighted imaging (IVIM-DWI) parameters distinguish kidney allografts with delayed graft function

Eyesha Hashim1, Darren Yuen2,3, General Leung1,4, and Anish Kirpalani1,4

1Medical Imaging, St. Michael's Hospital, Toronto, ON, Canada, 2Nephrology, St. Michael's Hospital, Toronto, ON, Canada, 3Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada, 4Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada

Delayed graft function (DGF) complicates 21-36% of all deceased donor kidney transplants, and leads to early inpatient post-transplant dialysis, higher risk of graft failure and death. In this abstract, we show that IVIM-derived flow (f)-fraction, is significantly different in kidney allografts exhibiting DGF compared to those that do not develop DGF. Furthermore, f fraction shows a significant negative correlation with time to recovery and a positive trend with renal function at 3 months post-transplant as measured with eGFR.

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