Abstract #2491

Intravoxel incoherent motion-diffusion weighted imaging (IVIM-DWI) parameters distinguish kidney allografts with delayed graft function

Eyesha Hashim¹, Darren Yuen^2,3, General Leung^1,4, and Anish Kirpalani^1,4

¹Medical Imaging, St. Michael's Hospital, Toronto, ON, Canada, ²Nephrology, St. Michael's Hospital, Toronto, ON, Canada, ³Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada, ⁴Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada

Delayed graft function (DGF) complicates 21-36% of all deceased donor kidney transplants, and leads to early inpatient post-transplant dialysis, higher risk of graft failure and death. In this abstract, we show that IVIM-derived flow (f)-fraction, is significantly different in kidney allografts exhibiting DGF compared to those that do not develop DGF. Furthermore, f fraction shows a significant negative correlation with time to recovery and a positive trend with renal function at 3 months post-transplant as measured with eGFR.

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