Abstract #2551

Magnetisation transfer in human liver and kidney through acquisition of the z-spectrum

Andrew John Carradus¹, Simon Shah¹, Olivier Mougin¹, Caroline Hoad^1,2, and Penny Gowland¹

¹Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, ²National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham, United Kingdom

This study explores the feasibility of measuring magnetisation transfer in both the liver and kidney through acquisition of a full z-spectrum. In this study we developed a protocol to reduce artefacts from respiration and blood flow pulsatility and measured relative amounts of MT in both the liver and kidney medulla by modelling MT with a super-Lorentzian lineshape and fitting to the acquired spectrum. This will be relevant in monitoring fibrosis in abdominal organs.

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