In this study we evaluated the utility of bolus-only ECV maps in extra-cardiac AL amyloidosis by comparing it with SAP scintigraphy findings in liver and spleen. These two techniques where performed in a large prospective cohort of patients with suspected systemic AL amyloidosis and where compared in terms of (1) diagnostic accuracy in liver and spleen amiloidosis; (2) quantification of the liver and spleen amyloid deposits. This was done using a standard acquisition for cardiac studies, with no extra image acquisition or optimization for hypochondriac regions.
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