Abstract #2557

Whole-body MRI for prostate cancer at primary staging: interobserver concordance, diagnostic accuracy and protocol optimisation

Edward William Johnston¹, Arash Latifoltojar¹, Harbir Sidhu¹, Elisenda Bonet-Carne¹, Magdalena Sokolska¹, Alan Bainbridge¹, and Shonit Punwani¹

¹Centre for Medical Imaging, University College London, London, United Kingdom

Whole body (WB) MRI is developing as a cancer staging platform in primary prostate cancer, although has not yet been adopted into clinical practice. In this study, we show that WB-MRI provides high levels of interobserver concordance, intermodality concordance and diagnostic accuracy for both nodal and metastatic bone disease, with higher levels of sensitivity than BS for metastatic disease, and similar performance to PET/CT. We also show that T2W and post contrast mDixon have no additive diagnostic value above T1W and DWI alone.

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