Abstract #2558

Image quality of WB-MRI in staging recurrent prostate cancer: a multicentre, multinational, multivendor, multiscanner study.

Edward William Johnston¹, Alan Bainbridge¹, Glenn Bauman², Sue Chua³, Ian Davis⁴, Rod Hicks⁵, Ur Metser⁶, Frederic Pouliot⁷, Andrew Scott⁸, Jonathan Thiessen², Nina Tunariu³, Andrew Weickhardt⁸, Louise Emmett⁹, and Shonit Punwani¹

¹Centre for Medical Imaging, University College London, London, United Kingdom, ²London Health Sciences Centre, London, ON, Canada, ³Royal Marsden Hospital, Sutton, United Kingdom, ⁴Monash, Melbourne, Australia, ⁵Peter McCallum Cancer Centre, Melbourne, Australia, ⁶University of Toronto, Toronto, ON, Canada, ⁷Laval Quebec, Quebec, QC, Canada, ⁸Olivia Newton-John Cancer Centre, Melbourne, Australia, ⁹St Vincents Cancer Center, Sidney, Australia

Whilst whole body (WB) MRI offers substantial promise in cancer staging, considerations regarding image quality are lacking in the literature, yet are essential for the effective delivery of the technique. Here we report the image quality of WB-MRI in 86 patients with suspected biochemical recurrence in prostate cancer in a trial carried out over 3 continents (Australia, America and Europe). We show that the image quality of WB-MRI varies substantially between anatomical sites and centres, particularly for diffusion-weighted sequences, which emphasizes the need to optimise sequences carefully prior to establishing a WB-MRI practice.

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