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Abstract #2558

Image quality of WB-MRI in staging recurrent prostate cancer: a multicentre, multinational, multivendor, multiscanner study.

Edward William Johnston1, Alan Bainbridge1, Glenn Bauman2, Sue Chua3, Ian Davis4, Rod Hicks5, Ur Metser6, Frederic Pouliot7, Andrew Scott8, Jonathan Thiessen2, Nina Tunariu3, Andrew Weickhardt8, Louise Emmett9, and Shonit Punwani1

1Centre for Medical Imaging, University College London, London, United Kingdom, 2London Health Sciences Centre, London, ON, Canada, 3Royal Marsden Hospital, Sutton, United Kingdom, 4Monash, Melbourne, Australia, 5Peter McCallum Cancer Centre, Melbourne, Australia, 6University of Toronto, Toronto, ON, Canada, 7Laval Quebec, Quebec, QC, Canada, 8Olivia Newton-John Cancer Centre, Melbourne, Australia, 9St Vincents Cancer Center, Sidney, Australia

Whilst whole body (WB) MRI offers substantial promise in cancer staging, considerations regarding image quality are lacking in the literature, yet are essential for the effective delivery of the technique. Here we report the image quality of WB-MRI in 86 patients with suspected biochemical recurrence in prostate cancer in a trial carried out over 3 continents (Australia, America and Europe). We show that the image quality of WB-MRI varies substantially between anatomical sites and centres, particularly for diffusion-weighted sequences, which emphasizes the need to optimise sequences carefully prior to establishing a WB-MRI practice.

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