Abstract #2560

Performance of PIRADSv2 ≥3 and ≥4 scores as cut-offs for the detection of prostate cancer

Chandan J Das¹, Vivek Lanka¹, Sanjay Sharma¹, Rishi Nayyar², and Virendra Kumar³

¹Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India, ²Department of Urology, All India Institute of Medical Sciences, New Delhi, India, ³Department of NMR, All India Institute of Medical Sciences, New Delhi, India

We report a prospective evaluation of prostate imaging reporting, archiving and data system version 2 (PIRADSv2) for multiparametric MRI (mpMRI) taking histopathology of radical prostatectomy specimens as reference standard. PIRADSv2 for mpMRI is easy to apply for detection of cancer of prostate (CaP) at optimal cut-offs of ≥3 for cancer as a whole and ≥4 for intermediate and high grade cancers. It is an accurate system to diagnose clinically significant disease. 26 patients having a biopsy-proven CaP, were investigated at 3.0T using mpMRI, followed by radical prostatectomy within 1 month. Gleason grade group from radical prostatectomy specimens and ROC curve analysis was used to determine the accuracy for cut-offs for scores of PIRADSv2.

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