Abstract #2580

Validation of magnetic resonance imaging-proton density fat fraction for hepatic fat content in healthy Asian population

Sonal Krishan¹

¹Radiology, Medanta Hospital, Gurgaon, India

The primary purpose of this work was to determine the precision of clinical MR imaging-PDFF hepatic fat quantification, to look at spatial heterogeneity in all the Couinad segments, to establish normative data and least significant change in Indian population. Our study has shown that there is no systematic or significant difference in the right versus left lobe, or any of the liver segments in patients with grade 0 steatosis. The least significant change of liver fat that can be measured reliably using MR imaging-PDFF is 2.1%. Mean hepatic fat content calculated by MR imaging-PDFF is 2.89% (95%CI, 1% - 6.8%) in normal Indian population.The current study is the first study determining normative data of hepatic fat content in histologically proven grade 0 steatosis population from India.

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