Abstract #2594

Assessment of Treatment Outcome in Chronic Hepatitis C Virus Infected Patients with Liver Stiffness Measured by Magnetic Resonance Elastography

Stephan Rodrigo Marticorena Garcia¹, Heiko Tzschätzsch¹, Christian Althoff¹, Christian Burkhardt¹, Michael Dürr², Fabian Halleck², Klemens Budde², Korinna Jöhrens³, Bernd Hamm¹, Jürgen Braun⁴, Thomas Fischer¹, Ingolf Sack¹, and Jing Guo¹

¹Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ²Nephrology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ³Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

High-resolution stiffness maps of the liver and kidney transplant (KTx) were generated after direct-acting antiviral therapy using multifrequency magnetic resonance elastography (MRE) and tomoelastography data processing in KTx recipients with chronic hepatitis C infection. Changes in liver stiffness after viral clearance were related to the immediate reduction in the inflammatory response in the early period and were stable until one year after end of treatment. MRE promises to be an early predictor for therapeutic success in HCV treatment.

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