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Abstract #2604

Demonstration of linear correlation between R2* and liver iron concentration across multiple MR acquisition parameters at 1.5T and 3T.

Richard Hayden Jones1, Jason Bentley2, Valentina Taviani3, Diego Hernando4, Scott Reeder5, and Shreyas Vasanawala1

1Radiology, Lucile Packard Children's Hospital, Palo Alto, CA, United States, 2Stanford University of Medicine Quantitative Sciences Unit, Stanford University, Palo Alto, CA, United States, 3GE Healthcare, Sunnyvale, CA, United States, 4Radiology, Medical Physics, University of Wisconsin, Madison, WI, United States, 5Radiology, Biomedical Engineering, Medical Physics, University of Wisconsin, Madison, WI, United States

We demonstrate a robust linear relationship between the concentration of liver iron and R2* measurements taken in any liver segment, with various planes of acquisition, slice thickness, flip angle, and echo spacing at 1.5T or 3T. As compared with Ferriscan, R2* imaging is faster, lower-cost, and requires no post-processing, and has better geographic availability compared to the gold standard of superconducting quantum interference devices.

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