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Abstract #2610

Liver Fibrosis Detection and Staging: A Comparative Study of T1ρ MR Imaging and 2D Real-time Shear-wave Elastography

Ruo-kun Li1, Fu-hua Yan1, Xin-pin Ren2, and Wei-bo Chen3

1Radiology, Ruijin Hospital, Shanghai Jiaotong University School of Medcine, Shanghai, China, 2Ultrasound, Ruijin Hospital, Shanghai Jiaotong University of Medcine, Shanghai, China, 3Philips Healthcare, Shanghai, China

There was moderate positive correlation between fibrosis stage and T1ρ values (r=0.566; 95% CI 0.291-0.754; P<0.0001), and LS value (r=0.726; 95% CI 0.521-0.851; P=0.003). T1ρ values showed moderate positive correlations with LS values (r=0.693; 95% confidence interval [CI]: 0.472-0.832; P<0.0001). Areas Under ROC (AUROCs) were 0.861 (95% CI: 0.705-0.953) for SWE and 0.856 (95% CI: 0.698-0.950) for T1ρ (P = 0.940), 0.906 (95% CI: 0.762-0.978) for SWE and 0.849 (95% CI: 0.691-0.946) for T1ρ (P = 0.414), 0.870 (95% CI: 0.716-0.958) for SWE and 0.799 (95% CI: 0.632-0.913) for T1ρ (P = 0.422), and 0.846 (95% CI: 0.687-0.944) for SWE and 0.692 (95% CI: 0.517-0.835) for T1ρ (P = 0.137), when diagnosing liver fibrosis with ≥F1, ≥F2, ≥F3 and F4, respectively. There was moderate positive correlation between inflammatory activity and T1ρ values (r=0.520; 95% CI 0.158-0.807; P=0.013).

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