Abstract #2612

Bi-exponential T1rho Relaxation of In Vivo Human Liver

Weitian Chen¹, Vincent Wong², Queenie Chan³, Yi-Xiang Wang¹, and Winnie Chu¹

¹Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, Hong Kong, ²Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, ³Philips Healthcare, Hong Kong, China, Shatin, Hong Kong

Quantitative T1rho imaging is reported a promising non-invasive diagnostic tool for detection of liver fibrosis at its early stage. T1rho relaxation is often estimated by a mono-exponential relaxation model. However, bi-exponential relaxation may occur due to compartmentation of the liver tissue. Bi-exponential T1rho relaxation has been reported in rat muscle and human knee cartilage. In this work, we provided our observation and analysis of bi-exponential T1rho relaxation of in vivo human liver.

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