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Abstract #2764

Improved ADC Estimation Technique Using Regularized Nonlinear Least Squares Fitting

Eric A. Borisch1, Adam T. Froemming1, Roger C. Grimm1, Yunhong Shu1, Ashley T. Tao1, Stephen J. Riederer1, and Joshua D. Trzasko1

1Radiology, Mayo Clinic, Rochester, MN, United States

A high-performance model-based regularized non-linear-least-squares ADC fitting technique has been designed and implemented. Phantom testing shows a reduction in noise with significant retention of detail, while providing < 10 sec computation for 3D acquisitions with 4 b-values.

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