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Abstract #2767

Joint T1/T2 mapping with frequency-modulated SSFP, radial sampling, and subspace reconstruction

Volkert Roeloffs1, Jost M. Kollmeier1, Nick Scholand2,3, Dirk Voit1, Sebastian Rosenzweig2,3, H. Christian M. Holme2,3, Martin Uecker2,3, and Jens Frahm1,3

1Biomed NMR, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany, 2Institute for Diagnostic and Interventional Radiology, University Medical Center, Goettingen, Germany, 3Partner site Goettingen, German Centre for Cardiovascular Research (DZHK), Goettingen, Germany

In this work, we propose frequency-modulated SSFP imaging with 3D stack-of-stars encoding to perform joint T1/T2 mapping. In contrast to phase-cycled SSFP, inefficient preparation phases are avoided and a subspace-constrained reconstruction allows efficient handling of large data sets. Quantitative mapping is realized by projecting the reconstructed subspace coefficients onto a precomputed piece-wise linear approximation of the Bloch-response manifold. General feasibility is proven by comparison to Gold Standard measurements on a home-brew T1/T2 phantom. The investigated approach is a promising candidate for multi-parametric mapping in vivo.

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