Abstract #2767

Joint T1/T2 mapping with frequency-modulated SSFP, radial sampling, and subspace reconstruction

Volkert Roeloffs¹, Jost M. Kollmeier¹, Nick Scholand^2,3, Dirk Voit¹, Sebastian Rosenzweig^2,3, H. Christian M. Holme^2,3, Martin Uecker^2,3, and Jens Frahm^1,3

¹Biomed NMR, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany, ²Institute for Diagnostic and Interventional Radiology, University Medical Center, Goettingen, Germany, ³Partner site Goettingen, German Centre for Cardiovascular Research (DZHK), Goettingen, Germany

In this work, we propose frequency-modulated SSFP imaging with 3D stack-of-stars encoding to perform joint T1/T2 mapping. In contrast to phase-cycled SSFP, inefficient preparation phases are avoided and a subspace-constrained reconstruction allows efficient handling of large data sets. Quantitative mapping is realized by projecting the reconstructed subspace coefficients onto a precomputed piece-wise linear approximation of the Bloch-response manifold. General feasibility is proven by comparison to Gold Standard measurements on a home-brew T₁/T₂ phantom. The investigated approach is a promising candidate for multi-parametric mapping in vivo.

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