In most diffusion studies, two or more DW images are acquired and an apparent diffusion coefficient (ADC) map is generated, with the goal of providing quantitative diffusion information that is independent of acquisition settings or secondary tissues properties. However, ADC values can vary significantly following protocol changes. In this work, we analytically determine the statistical bias in ADC maps generated from multi-point DWI acquisitions, and show how the derived model rationalizes noise-based error propagation as the source of ADC inconsistencies observed in our own clinical practice.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords