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Abstract #2771

The change in R2* with PDFF in liver can be explained by the water/fat susceptibility difference

Mark Bydder1, Ludovic de Rochefort1, Gavin Hamilton2, Nikolaus Szeverenyi2, and Claude Sirlin2

1Aix Marseille University, Marseille, France, 2University of California San Diego, San Diego, CA, United States

Proton density fat fraction (PDFF) measurements can be confounded by small effects that are not properly accounted for in modeling. This abstract seeks to understand the empirically observed correlation between R2* and PDFF in terms of the susceptibility difference between water and fat. Numerical fitted values were found to be close to literature values for triglyceride unsaturation and magnetic susceptibility in liver.

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