The exposure of blood serum to reactive oxygen species creates free radicals and damages the structure of biomolecules. It causes proton NMR relaxation times to change over time. In aqueous protein solutions, T1 and T2 decay curves were fitted by single exponential components. Following addition of hydrogen peroxide to blood serum which contained endogenous antioxidants, relaxation times initially decreased then increased towards initial values. The character of these curves and their fitting parameters depend on kinetics of oxidation processes. We hope that MR imaging may help to investigate these important processes also in vivo.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords