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Abstract #2902

Comparison of GRE, SSFP, and CINE CMR Acquisitions for Measuring Magnetization Transfer at 3T

Matthew Jacob Van Houten1, Yang Yang1, and Michael Salerno1

1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States

We developed and compared multiple magnetization transfer (MT) pulse sequence strategies to characterize myocardial fibrosis without the need for gadolinium contrast at 3T. We demonstrated in an initial study of 4 healthy volunteers that a free-breathing, single-shot GRE is the most effective technique for producing high quality myocardial MT ratio maps. We will continue refining and investigating this sequence as a method for quantifying both focal and diffuse fibrosis in patients with heart failure.

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