Current standard myocardial T1 mapping is based on the modified Look-Locker inversion recovery (MOLLI) technique and single-shot readout per image acquisition. A second-based scheme has recently been proposed to mitigate the dependence of imaging times on heartrate and also to increase robustness in T1 estimation. Here we report a phantom-based study with ECG simulation comparing it with the original beat-based MOLLI acquisition scheme at both 1.5 and 3.0T. We demonstrate the advantage of this approach with reduced heartrate dependence and variation for an improved T1 quantification reliability.
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