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Abstract #2921

Understanding the material behaviour of ex-vivo porcine hearts using MR-Elastography and Rheology

Myrianthi Hadjicharalambous1, Adela Capilnasiu1, Ayse Sila Dokumaci1, Daniel Fovargue1, Gerhard Sommer2, Gerhard Holzapfel2, Ralph Sinkus1, and David Nordsletten1

1Biomedical Engineering, King's College London, London, United Kingdom, 2Institute of Biomechanics, Graz University of Technology, Graz, Austria

Myocardial stiffness has been shown to correlate with heart disease, nevertheless, reliable stiffness estimates are hindered by the remarkably complex behaviour and function of the heart muscle. In this work, we use MR-Elastography and rheological experiments to obtain a better understanding of the myocardial material behaviour. MR-Elastography and cyclic shear tests are performed on ex-vivo porcine hearts, under varying frequencies. Our results demonstrate important tissue properties and highlight the viscoelastic properties of the myocardium which are often neglected. Improving our understanding of the interlinked material properties of the heart is a critical step towards the accurate prediction of myocardial stiffness.

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