Abstract #2925

Fast Self-Navigated Wall Shear Stress Measurements in the Murine Aortic Arch Using Radial 4D-PC-MRI at 17.6T

Kristina Andelovic^1,2, Patrick Winter², Thomas Kampf^2,3, Julius Heidenreich³, Anton Xu², Peter M. Jakob², Wolfgang R. Bauer¹, and Volker Herold²

¹Medicine I, Cardiology, University Hospital Wuerzburg, Wuerzburg, Germany, ²Experimental Physics V, University of Wuerzburg, Wuerzburg, Germany, ³Interventional and Diagnostic Radiology, University Hospital Wuerzburg, Wuerzburg, Germany

4D phase contrast (PC)-MRI is a non-invasive tool for the assessment of cardiovascular hemodynamics or the Wall Shear Stress (WSS) to study atherosclerotic risks in vivo. Major limitations of conventional triggered methods are the long measurement times needed for high-resolution data sets and the requirement of stable ECG triggering, which is diffcult at high magnetic field strengths. In this work, an ECG-free, retrospectively synchronized method is presented that enables fast high-resolution measurements of 4D flow and wall shear stress in the murine aortic arch.

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